The extract of peanut shell enhances neurite outgrowth of neuronal cells: Recycling of agricultural waste for development of nutraceutical products

Journal of Functional Foods(2022)

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摘要
•PSE induced the differentiation of PC12 cells, SH-SH5Y cells, and primary cultured neurons.•PSE activated the phosphorylation of ERK1/2 and Akt.•PSE synergistically works with neurotrophic factors in inducing the neurite outgrowth.•Luteolin, eriodictyol and 5,7-dihydroxychromone account for the function of PSE.
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关键词
Agricultural waste,Peanut shell,Flavonoid,Luteolin,Neurite outgrowth,Neurotrophic factor
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