Antinociceptive and anti-inflammatory activities of ethanol-soluble acidic component from Ganoderma atrum by suppressing mannose receptor

Yu-Fei Yao,Le-Feng Wang,Su-Mei Chen,Rui-Ting Wu, Fei-Yue Long,Wen-Juan Li

Journal of Functional Foods（2022）

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摘要

•The antinociceptive and anti-inflammatory activities of ESAC was observed.•ESAC-mediated antinociceptive effects were related to anti-inflammatory activities.•Opiate receptors were linked to the analgesic effect of ESAC in mice.•MR acted as vital roles for ESAC to execute anti-inflammatory response in macrophages.

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关键词

Ganoderma atrum,Ethanol-soluble acidic component,Analgesic effect,Anti-inflammatory effects,Mannose receptor

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