Low toxicity of metal-organic framework MOF-199 to bacteria Escherichia coli and Staphylococcus aureus

Bowei Ouyang,Peng Ouyang,Mengyao Shi,Tusunniyaze Maimaiti,Qun Li,Suke Lan,Jin Luo,Xian Wu,Sheng-Tao Yang

Journal of Hazardous Materials Advances（2021）

Cited 9|Views6

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Abstract

•Metal-organic framework (MOF) showed low toxicity to bacteria only at high concentrations.•MOF-199 was more toxic to Escherichia coli than Staphylococcus aureus.•The toxicological mechanism of MOF-199 included the membrane damage and oxidative stress.•The toxicity was partially from the release of Cu2+ of MOF-199.

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Key words

Metal-organic framework,Bacteria,Toxicity,DNA damage,Oxidative stress,Environmental safety

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