Investigation on co-solvency, solvent effect, Hansen solubility parameter and preferential solvation of fenbufen dissolution and models correlation
Journal of Molecular Liquids(2022)
Abstract
•Solubility of fenbufen in different mono-solvents and mixture solvents was determined.•Preferential solvation of fenbufen in mixture solvents was investigated by IKBI method.•Molecular interactions were discussed by solvent effect using KAT-LSER model.•Use Hansen solubility parameter to evaluate the dissolve ability of solvents to fenbufen and co-solvency phenomenon.•Different thermodynamics models were used to correlate the solubility data.
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Key words
Fenbufen solubility,Cosolvency phenomenon,Solvent effect,Hansen solubility parameter,Preferential solvation,Model correlation
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