One-pot synthesis of dihydropyrimidines via eco-friendly phosphorus derivatives catalysis

Zakaria Moutaoukil,Cyril Ronco,Rachid Benhida

Journal of Saudi Chemical Society（2022）

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摘要

•Screening of phosphate derivatives as inexpensive and eco-friendly catalysts.•Efficient catalysis by widely available hypophosphorous acid H3PO2.•Straightforward high-yielding synthesis of dihydropyrimidines.•Access to original related heterocyclic scaffolds.

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关键词

Phosphate derivatives catalysis,Biginelli reaction,Dihydropyrimidines,One-pot protocol,Fused heterocycles

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