Limiting Dilution Tumor Initiation Assay: An In Vivo Approach for the Study of Cancer Stem Cells.

Petra den Hollander,Robiya Joseph,Suhas Vasaikar,Nick A Kuburich,Abhijeet P Deshmukh,Sendurai A Mani

Methods in molecular biology (Clifton, N.J.)（2022）

Cited 3|Views45

No score

Abstract

Cancer stem cells (CSCs) are a small subpopulation of self-renewing cancer cells that are present within tumors. Calculating the frequency of tumor-initiating cells is important in the assessment of the number of CSCs present in a cell population. In this chapter, we present a protocol developed for quantification of CSCs from breast cancer tumors that can be adapted to CSCs from other types of tumors.

Translated text

Key words

Cancer stem cells,In vivo,Limiting dilution tumor initiation,Tumor-initiating cell frequency

AI Read Science

Must-Reading Tree

Example

Generate MRT to find the research sequence of this paper

Chat Paper

Summary is being generated by the instructions you defined