Antenatal intravenous immunoglobulins in pregnancies at risk of fetal and neonatal alloimmune thrombocytopenia: comparison of neonatal outcome in treated and nontreated pregnancies

Siw L Ernstsen,Maria T Ahlen, Tiril Johansen, Eirin L Bertelsen,Jens Kjeldsen-Kragh,Heidi Tiller

American Journal of Obstetrics and Gynecology（2022）

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摘要

The most reliable data hitherto for the evaluation of intravenous immunoglobulins treatment in low-risk pregnancies is shown herein. We did not find evidence that omitting antenatal intravenous immunoglobulin treatment in low-risk pregnancies increases the risk of neonatal intracranial hemorrhage.

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关键词

alloimmunization,antenatal management,human platelet antigen 1a,intracranial hemorrhage,intravenous immunoglobulins,neonatal alloimmune thrombocytopenia,newborn

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