Quantification of brain age using high-resolution 7 tesla MR imaging and implications for patients with epilepsy

•A regression-based model used 7T MRI imaging metrics to predict brain age.•Mean absolute error of 6.6 years with 0.0 years brain-PAD in healthy controls.•Brain-PAD of +5.0 years in non-lesional epilepsy cohort, despite similar accuracy.•Significantly greater brain-PAD epilepsy patients compared to controls (p = 0.0007).•Differences in brain-PAD greater in patients with high seizure frequency.