Perioperative Safety Evaluation of Gastrointestinal Surgery in Patients With Prosthetic Valves

Background: In patients with prosthetic valves, the perioperative outcomes, as well as the risk factors, following gastrointestinal surgery remain to be defined. Methods: From January 2010 to March 2018, the clinical data of 69 cases with prosthetic valves after gastrointestinal surgery retrospectively were collected. Univariate and multivariate analysis were applied to identify the risk factors associated with significant bleeding events and non-hemorrhagic complications. Results: Among 69 cases, 9 patients (13.0%) presented major bleeding events, and 21 patients (30.4%) presented non hemorrhagic complications. Major bleeding events were significantly higher in patients with simple aortic valve replacement (AVR) than in other types of prosthetic valves (27.6% vs. 2.5%, P = 0.003), and there was no significant difference in the incidence of non-hemorrhagic complications. Simple AVR was the significant risk factor for major bleeding events (P = 0.043). Significant risk factors for non-hemorrhagic complications were operative duration >= 160 minutes (P = 0.021), duration from heart valve replacement to gastrointestinal surgery >= 84 months (P = 0.039), and simple AVR (P = 0.047). Conclusion: The patients with simple AVR had a much higher bleeding risk following gastrointestinal surgery.