ATP7A, ATP7B, and RETN genotypes in Labrador Retrievers with and without copper-associated hepatopathy.

Daniel K Langlois, Brendan S M Nagler,Rebecca C Smedley,Ya-Ting Yang,Vilma Yuzbasiyan-Gurkan

Journal of the American Veterinary Medical Association（2022）

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摘要

Study results supported a contributory role for the ATP7B variant in CAH pathogenesis in Labrador Retrievers. However, the application of genetic testing in a clinical setting is complicated by genotypic variability within healthy and diseased dogs.

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