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Construction of Molecular Robots from Microtubules for Programmable Swarming.

Methods in molecular biology (Clifton, N.J.)(2022)

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Abstract
Swarm robotics has been attracting much attention in recent years in the field of robotics. This chapter describes a methodology for the construction of molecular swarm robots through precise control of active self-assembly of microtubules (MTs). Detailed protocols are presented for the construction of molecular robots through conjugation of DNA to MTs and demonstration of swarming of the MTs. The swarming is mediated by DNA-based interaction and photoirradiation which act as processors and sensors respectively for the robots. Furthermore, the required protocols to utilize the swarming of MTs for molecular computation is also described.
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Key words
DNA Programming,Kinesin,Microtubule,Molecular robot,Photoresponsive DNA,Swarming
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