Germline mutations in penetrant cancer predisposition genes are rare in men with prostate cancer selecting active surveillance.
Cancer medicine（2022）
摘要
The frequency of pathogenic germline mutations in penetrant cancer predisposition genes is extremely low in men with PC undergoing active surveillance and pathogenic germline mutations had no apparent association with grade reclassification or adverse characteristics.
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关键词
active surveillance,adverse pathology,germline mutations,prostate cancer
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