Investigation of early biochemical alterations in myocardia of the diabetic db/db mice by FTIR microspectroscopy combined with machine learning
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy（2022）
Abstract
•FTIRM was used to elucidate the DbCM process.•Biochemical alterations in diabetic myocardia were detected by FTIRM.•A RF classifier was built for diagnosing DbCM with 97.1% accuracy.
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Key words
Diabetic cardiomyopathy,Fourier transform infrared microspectroscopy,Db/db mice,Machine learning
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