Intact Quantitative Bioanalytical Method Development and Fit-for-purpose Validation of a Monoclonal Antibody and Its Related Fab Fragment in Human Vitreous and Aqueous Humor Using LC-HRMS.
Analytical and bioanalytical chemistry/Analytical & bioanalytical chemistry(2022)
Key words
Bevacizumab,Ranibizumab,VEGF,LC-HRMS,Bioanalytical method development,Monoclonal antibody,Intact protein quantitation,Orbitrap,Deconvolution,Top-down
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