The applicability of the digit wrinkle scan to quantify sympathetic nerve function

Maurice Sopacua,Carla M L Gorissen-Brouwers,Bianca T A de Greef,Isis B T Joosten,Catharina G Faber,Ingemar S J Merkies,Janneke G J Hoeijmakers

Clinical Neurophysiology Practice（2022）

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摘要

•Normative values for stimulated skin wrinkling are age-dependent.•Stimulated skin wrinkling has never been evaluated quantitatively.•The clinical application of the stimulated skin wrinkling in an ordinal fashion is doubtful.

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关键词

5-point scale,Digit wrinkle scan,Small fiber neuropathy,Autonomic function,Digit vasoconstriction,Inter-observer reliability

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