Iodine-mediated oxythiolation of o-vinylanilides with disulfides for the synthesis of benzoxazines

RSC ADVANCES(2022)

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Abstract
An efficient iodine-mediated oxythiolation of o-vinylanilides with disulfides was developed. By virtue of this method, a series of thio-tethered benzoxazine derivatives were synthesized in good to excellent yields. The reaction features high yields, is metal-free, and has a wide substrate scope.
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Key words
benzoxazines,disulfides,synthesis,oxythiolation,iodine-mediated
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