Neutrophils flash their GLUTs to beat back detestable fungi
Cell Host & Microbe（2022）
摘要
Neutrophils enforce frontline immunity to fungal infection. Potent neutrophil effector functions require vast amounts of cytosolic glucose. Li et al. describe how neutrophils, upon interaction with Candida albicans, modulate the new synthesis and membrane localization of Glucose Transporter 1 (GLUT1) to facilitate glucose entry and meet neutrophils' metabolic needs.
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