Navigating EMT with COMPASS and PRC2
NATURE CELL BIOLOGY(2022)
Abstract
Epithelial to mesenchymal transitions (EMTs) drive cancer metastases. A series of single cell analyses now reveal this change in state is not binary and that two epigenetic complexes govern the convertibility of epithelial cells to mesenchymal states that are differentially conducive to metastasis.
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Key words
Breast cancer,Chromatin remodelling,Metastasis,Life Sciences,general,Cell Biology,Cancer Research,Developmental Biology,Stem Cells
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