Adding a New Dimension to the Amorphous Solid Dispersion Phase Diagram: Studying Dissolution Kinetics of Crystalline Drugs in a Polymer Matrix Using Temperature Dependent XRPD and DSC
Journal of Pharmaceutical Sciences（2022）
Key words
Dissolution kinetics,Particle size effect,Amorphous solid dispersions,Hot melt extrusion,Phase diagram,Process operating design space,Acetaminophen,Indomethacin,DSC,Temperature dependent XRPD
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