Tear Film Immunological Profile in Patients with Ocular Graft versus Host Disease.

Patricia Serapicos, Cinthia Kim, Sabrina Leite Barros, Isa Maria Bastos Mendes Silva Jordão,Meire Ioshie Hiyane,Luciene Barbosa de Sousa,Victor Gottardello Zecchin,Niels Olsen Saraiva Camara,Lauro Augusto de Oliveira

Ocular immunology and inflammation（2022）

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摘要

We demonstrated higher tear levels of IL-8 and MIP-1α in oGVHD patients and significant correlations between theses cytokines and ocular surface parameters based on the ICCGVHDCG criteria.

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关键词

Allogeneic bone marrow transplantation,dry eye disease,graft-versus-host disease,hematopoietic stem cells,ocular GVHD,ocular surface disease,tear film biomarker

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