In a Pinch: Cefiderocol for CRAB Infections COMMENT
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY(2022)
Abstract
Carbapenem-resistant Acinetobacter baumannii (CRAB) can cause significant infections with limited treatment options available. Falcone et al. (https://doi.org/10.1128/aac.02142-21) describe a single-center retrospective study comparing clinical outcomes among patients with CRAB infections treated with cefiderocol-containing versus colistin-containing regimens. Patients who received cefiderocol-containing regimens had lower 30-day mortality, though there are several limitations raised here, which make interpretation and applicability difficult.
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Key words
Acinetobacter, CRAB, cefiderocol
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