The correlation between genetic factors and freezing of gait in patients with Parkinson's disease

Parkinsonism & Related Disorders(2022)

Cited 1|Views17
No score
Abstract
•Clinical-related risk factors to freezing of gait (FOG) in Parkinson's disease (PD) have been identified.•The influence of genetic variations on the FOG occurrence has been poorly studied thus far.•Genetic variants in dopamine-related genes might play a role in the FOG occurrence.•AA rs4680 COMT might contribute to FOG development among PD patients.•AGGAA and GGAAA haplotypes could act as protective and vulnerability factors for FOG occurrence.
More
Translated text
Key words
Parkinson's disease,Freezing of gait,Risk factors,Genetic polymorphisms,DRD2,COMT Val158Met
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined