Effects of Curcumin-mediated photodynamic therapy on autophagy and epithelial-mesenchymal transition of lung cancer cells
Photodiagnosis and Photodynamic Therapy（2022）
Abstract
•Curcumin-mediated PDT inhibited EMT, migration and invasion of lung cancer cells.•Curcumin-PDT induced autophagy in lung cancer cells.•Autophagy was involved in the process of Curcumin-PDT inhibiting EMT, but it presented a promoting effect of EMT in lung cancer cells.•Curcumin-PDT combined with autophagy inhibitor further inhibited EMT of lung cancer cells.
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Key words
Lung cancer,Curcumin,Photodynamic therapy,autophagy,Epithelial-mesenchymal transition,Metastasis
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