Notopterygium incisum Root Extract (NRE) Alleviates Epileptiform Symptoms in PTZ-Induced Acute Seizure Mice.

Lijun Zhou,Yaping Gao,Hongyuan Lu,Wenwu Liu,Xiangbo Xu,Bo Xing,Xu Liang,Nan Wang,Xiaowen Jiang,Qingchun Zhao

CNS & neurological disorders drug targets（2023）

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摘要

This study suggests that NRE can alleviate epilepsy and improve cognitive function in mice with epilepsy, and its mechanism may be through reducing inflammation and enhancing antioxidant defense.

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关键词

Epilepsy,Immunohistochemistry (IHC),Notopterygium incisum,PTZ,neuroinflammation,oxidative status

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