Picomolar Sensitivity Analysis of Multiple Bradykinin-Related Peptides in the Blood Plasma of Patients With Hereditary Angioedema in Remission: A Pilot Study.

François Marceau,Georges-Etienne Rivard,Jacques Hébert, Julie Gauthier,Hélène Bachelard,Tanja Gangnus,Bjoern B Burckhardt

Frontiers in allergy（2022）

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摘要

BK, BK and the sum of BK and its fragments determined by the sensitive LC-MS/MS technique are proposed as potential biomarkers of HAE-C1INH in remission while this was not applicable to HAE-FXII patients.

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关键词

F12 variant,LC-MS/MS,SERPING1 variants,bradykinin,hereditary angioedema

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