Virtual screening of molecular databases for potential inhibitors of the NSP16/NSP10 methyltransferase from SARS-CoV-2

•Virtual screening by Docking using different molecular databanks in the search of potential inhibitors of NSP16-NSP10 protein dimer from SARS-CoV-2;•Evaluation of the physicochemical and ADMET properties of the most promising ligands showed interesting results;•Encouraging of future pharmacological tests with the compounds identified with higher affinity, as well exploring the other molecular scaffolds evidenced;