Insulin resistance and miR-143/miR-145 relative expression profile is associated with dysregulation in the pathological adiposity setting in aging

Objective: Insulin resistance take a crucial role in metabolism. Also, the presence of microRNAs was involved in metabolic control. Remarkably, circulating miR-143 and miR-145 have shown controversial results regarding women-metabolism in the aging process. Our study aimed to evaluate the association of metabolic profile with the relative expression of circulating miR-143 and miR-145 in the insulin resistance pathological adiposity in the elderly women group.