A derivatization-based densitometric method for simultaneous estimation of artemether and lumefantrine: Method development, validation and applications

Ripandeep Kaur,O.P. Katare,Guneet Singh, Vishav Mohan,Sumant Saini,Bhupinder Singh

Microchemical Journal（2021）

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摘要

•Intranasal nanolipidic micelles-based Co-delivery of Artemether-Lumefantrine (AM-LMF).•Robust method for simultaneous analysis of AM & LMF in various sample types.•Validation of developed method as per ICH Q2R1 guidelines.•Application of developed method in quantifying drug levels in brain.

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关键词

HPTLC,Analytical validation,Brain,Intranasal,Simultaneous estimation,Densitometry

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