lncRNA TM4SF1-AS1 predicts dismal outcomes and promotes cholangiocarcinoma progression via modulating miR-744-3p

Hang Jiang, Wei Li, Zhiqian Xue, Wei Chen, Liping Zhao,Haihan Song,Jianhong Hou

Clinics and Research in Hepatology and Gastroenterology（2022）

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摘要

•lncRNA TM4SF1-AS1 was found to upregulate in cholangiocarcinoma and negatively correlated with the reduced expression of miR-744-3p.•TM4SF1-AS1 serves as a prognostic biomarker and tumor promoter of CCA predicating patients’ outcomes.•TM4SF1-AS1 accelerating tumor progression via modulating miR-744-3p.

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关键词

Cholangiocarcinoma,lncRNA TM4SF1-AS1,miR-744-3p,Tumor promoter,Prognostic biomarker

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