Mechanism Research of Platelet Core Marker Prediction and Molecular Recognition in Cardiovascular Events.

Combinatorial chemistry & high throughput screening(2023)

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摘要
VEGFA is most likely to reduce its expression by binding to ConA, which could affect the downstream regulation of the PI3K/Akt signaling pathway during platelet activation. Some other core targets also have the opportunity to interact with ConA to affect platelet-activated thrombosis and trigger changes in cardiovascular events.
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关键词
Cardiovascular diseases,enrichment analysis,gene regulation,molecular docking,platelet activation,sickle cell disease
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