Deep Brain Stimulation in a Patient with Parkinson's Disease and Cortical Superficial Siderosis

Makoto Shiraishi, Keita Matsuura, Yamato Nishiguchi, Akihiro Shindo, Tomohiro Araki, Hiroyuki Kajikawa, Yoshinari Nakatsuka, Munenari Ikezawa, Hidekazu Tomimoto

INTERNAL MEDICINE（2022）

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Abstract

Cortical superficial siderosis (cSS) is a rare condition that is regarded as a potential magnetic resonance marker of cerebral amyloid angiopathy (CAA). We describe the case of a 68-year-old man with cSS and Parkinson's disease (PD) who subsequently exhibited incidental microhemorrhages, which were only detected on magnetic resonance imaging (MRI), at one week after deep brain stimulation (DBS) surgery. cSS is now considered to be a significant risk factor for CAA and future bleeding. Therefore, because DBS surgery is in-vasive and may increase the risk of intracerebral hemorrhage, the procedure should be performed carefully when managing patients with PD and CAA.

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Key words

intracerebral hemorrhage,cortical superficial siderosis,cerebral amyloid angiopathy,Parkinson's disease,deep brain stimulation

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