Exposure to World Health Organization's AWaRe antibiotics and isolation of multidrug resistant bacteria: a systematic review and meta-analysis

Giorgia Sulis,Sena Sayood, Shashi Katukoori,Neha Bollam,Ige George,Lauren H Yaeger,Miguel A Chavez,Emmanuel Tetteh,Sindhu Yarrabelli,Celine Pulcini,Stephan Harbarth,Dominik Mertz,Mike Sharland,Lorenzo Moja,Benedikt Huttner,Sumanth Gandra

Clinical Microbiology and Infection（2022）

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摘要

Optimising use of Access antibiotics is likely to reduce the selection of MDROs and global antibiotic resistance. Despite data limitations, our study offers a strong rationale for further adoption of AWaRe as an important tool to improve antibiotic use globally.

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关键词

Antibiotic exposure,Antibiotic stewardship,AWaRe framework,Critical priority pathogens,High-priority pathogens,Multidrug resistant organisms,Resistance selection

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