The war against Alzheimer, the mitochondrion strikes back!

Kevin Zambrano,Diego Barba,Karina Castillo,Paola Robayo,Dariana Argueta-Zamora,Serena Sanon,Eduardo Arizaga,Andres Caicedo,Antonio W D Gavilanes

Mitochondrion（2022）

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摘要

•Mitochondria are pivotal players in the survival of central nervous system function.•“Mitochondrial dysfunction” is central to the pathogenesis of AD.•There is contrasting data regarding extracellular mitochondria concentration in AD.•Early studies on mitochondrial transplant have shown to strike back against AD.

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关键词

Extracellular mitochondria,Alzheimer’s disease,Neurodegenerative disease,Mitochondrial therapy,mtDNA

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