Antioxidant and Lipid Supplementation Improve the Development of Photoreceptor Outer Segments in Pluripotent Stem Cell-Derived Retinal Organoids

Emma L. West, Paromita Majumder,Arifa Naeem,Milan Fernando,Michelle O'Hara-Wright, Emily Lanning,Magdalena Kloc,Joana Ribeiro,Patrick Ovando-Roche,Ian O. Shum, Neeraj Jumbu,Robert Sampson, Matt Hayes,James W. B. Bainbridge,Anastasios Georgiadis,Alexander J. Smith,Anai Gonzalez-Cordero,Robin R. Ali

Stem Cell Reports（2022）

Cited 16|Views25

Key words

retinal organoids,outer segments,disease modeling,induced pluripotent stem cells,RPGR,gene therapy,photoreceptors,retinitis pigmentosa,degeneration,docosahexaenoic acid

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