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Continuous-flow synthesis of alkyl zinc sulfinates for the direct photofunctionalization of heterocycles

José Luis Nova-Fernández,Montaña J García,Leonardo Mollari,Gustavo Pascual-Coca,Silvia Cabrera,José Alemán

Chemical Communications（2022）

Cited 4|Views7
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Abstract
A sustainable strategy for the alkylation of heterocycles is presented. The protocol relies on the in situ generation and further in-line use of alkyl zinc sulfinates through a continuous-flow system. The environmentally friendly character of the protocol is assured by the use of a green solvent mixture, the presence of a metal free oxidant and low waste generation.
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Key words
alkyl zinc sulfinates,direct photofunctionalization,synthesis,continuous-flow
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