Clinical Outcomes of Postoperative Adjuvant Chemotherapy for Surgically Resected High-Grade Pulmonary Neuroendocrine Carcinoma.

Mie Kotake,Hisao Imai,Kyoichi Kaira,Hideki Endoh,Yutaka Yamada,Takayuki Kaburagi,Moriyuki Kiyoshima,Tomohide Sugiyama,Yoichi Nakamura,Takashi Kasai,Haruhisa Matsuguma,Hiroyuki Minemura,Kenya Kanazawa,Hiroyuki Suzuki,Atsushi Fujita,Koichi Minato

Chemotherapy（2022）

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摘要

Most patients with HGNEC received small-cell lung cancer-based regimens as postoperative adjuvant chemotherapy. Those who relapsed after adjuvant chemotherapy were mainly treated with amrubicin. Our findings suggest that platinum-doublet chemotherapy tends to improve the time to progression disease and overall survival in patients who relapse after postoperative adjuvant chemotherapy.

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关键词

Adjuvant chemotherapy,High-grade pulmonary neuroendocrine carcinoma,Overall survival,Relapse-free survival,Surgical resection

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