Universal Screening for Lynch Syndrome Compared with Pedigree-Based Screening: 10-Year Experience in a Tertiary Hospital.

Min Hyun Kim,Duck-Woo Kim,Hye Seung Lee, Su Kyung Bang,Soo Hyun Seo,Kyung Un Park,Heung-Kwon Oh,Sung-Bum Kang

Cancer research and treatment（2023）

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摘要

Despite widespread adoption of routine tumor testing for MSI, this is not a fail-safe approach to screen all LS patients. Obtaining a thorough family history in combination with universal screening provides a more comprehensive 'universal' screening method for LS.

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关键词

Colorectal neoplasms,Family history,Hereditary nonpolyposis colorectal cancer,Lynch syndrome,Pedigree,Universal screening

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