Bacillus -supplemented diet improves growth performance in Jeju native pigs by modulating myogenesis and adipogenesis.

Probiotics are used in pigs as nutritional supplements to improve health and induce the development of muscle and adipose tissue for enhancing growth performance and harvesting quality meat. In this study, we investigated the effects of -based probiotic supplementation on the physiological and biochemical changes in Jeju native pigs (JNPs), including growth performance, backfat layers, blood parameters, serum IgG levels, myogenic and adipogenic markers, and expression of inflammatory markers. Average daily gain and feed efficiency were higher in the diet group than in the basal diet group, while backfat thickness was lower in the diet group than in the basal diet group. Blood biochemical parameters and hematological profiles were not altered significantly by -based probiotic supplementation. Serum IgG concentration increased in the diet group compared to the basal diet group. The diet group showed increased adipogenic and myogenic markers expression in the muscle and adipose tissues. Overall, the data suggest that the -based probiotics-supplemented diet regulates myogenesis and adipogenesis in JNPs and improves growth performance. We postulate that this may be due to the changes in the gut microbiota of pigs due to probiotic supplementation.