Downregulation of the long non-coding RNA MALAT1 in tenofovir-treated pregnant women with hepatitis B virus infection promotes immune recovery of natural killer cells via the has-miR-155-5p/HIF-1α axis

•LncRNAs from transcriptome high-throughput sequencing in peripheral blood of pregnant women with HBV infection.•Find enriched function of lncRNA by gene set enrichment analysis.•Effects of lncRNA MALAT1 on NK cell-mediated immunity in TDF-treated pregnant women with HBV infection.•MALAT1 regulates has-miR-155-5p/HIF-1α axis.•Mechanism research about MALAT1 on cytokine secretion by NK cells.