Acute ophthalmic manifestations in Mycoplasma induced rash and mucositis

Abstract Background: The purpose of the current study is to demonstrate the prevalence of ocular complications in patients suffering with MIRM, an eruption clinically distinct from Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN).Methods: In this retrospective observational study, we identified all patients in our hospital database who were diagnosed with MIRM. Diagnosis was confirmed by clinical information and a positive Mycoplasma pneumoniae serology. Only patients with available records with formal ophthalmology consults were included. Clinical and laboratory data were collected from our electronic medical record system.Results: A total of 11 patients were included in our study. The average age was 22 ± 15.2 years, and the majority were male (63.6%). In all 22 eyes, the acute ocular findings were limited to conjunctival hyperemia (n=18, 81.8%), meibomitis (n=2, 9.1%), and conjunctival epithelial defects (n=1, 4.5%). None of the patients were treated with amniotic membrane transplantation in the acute phase. Three patients received follow-up eye examinations; none showed ocular complications.Conclusions: Ocular complications from MIRM appear to be milder in comparison to ocular complications found in other bullous and inflammatory conditions such as SJS/TEN. Understanding the ocular sequelae of MIRM is important to better inform acute and chronic management.