Epidemiology and prediction of multidrug-resistant bacteria based on hospital level

•Monthly hospital report data were used to identify indicators that are highly correlated with and predictive of multidrug-resistant bacteria (MDRB) infection.•The number of hospitalised patients who received emergency rescues and rate of rational perioperative antimicrobial drug use were correlated with the number of patients with MDRB infection after 1 to 2 months.•An early warning platform for patients with MDRB infection can be built using these monthly predictive indicators and their thresholds.•Predictive indicators include the number of hospitalised operations, the number of patients visited the community health services centers, the number of hospitalised patients who received emergency rescues, the rate of clinical pathways, and the number of discharged patients.