Experimental infection of mink with SARS-COV-2 Omicron (BA.1) variant leads to symptomatic disease with lung pathology and transmission

Jenni Virtanen,Kirsi Aaltonen,Kristel Kegler,Vinaya Venkat,Thanakorn Niamsap,Lauri Kareinen,Rasmus Malmgren,Olga Kivelä,Nina Atanasova,Pamela Österlund,Teemu Smura,Antti Sukura,Tomas Strandin,Lara Dutra,Olli Vapalahti,Heli Nordgren,Ravi Kant,Tarja Sironen

biorxiv（2022）

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摘要

We report an experimental infection of American mink with SARS-CoV-2 Omicron variant and show that minks remain virus RNA positive for days, develop clinical signs and histopathological changes, and transmit the virus to uninfected recipients warranting further studies and preparedness. ### Competing Interest Statement The authors have declared no competing interest.

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关键词

lung pathology,mink,experimental infection,symptomatic disease,sars-cov

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