Cascade Reaction by I 2 /Base‐Promoted Synthesis of Chromeno‐[3,4‐ c ]pyrrol‐4(2 H )‐ones from 2‐Hydroxychalcones and β‐ Enamine Esters
ChemistrySelect(2022)
Abstract
An efficient methodology for the synthesis of a variety of chromeno[3,4‐ c ]pyrrol‐4(2 H )‐ones from 2‐hydroxychalcones and N ‐substituted β ‐enamine esters via I 2 /base promoted Michael addition/cyclization/lactonization/aromatization sequence have been developed, affording the coumarin heterocyclic derivatives in moderate to excellent yields. This approach is a highly efficient and convenient way to get derivatives of chromeno[3,4‐ c ]pyrrol‐4(2 H )‐ones from readily accessible substrates under green reaction conditions.
MoreTranslated text
Key words
synthesis
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined