5-Indolylidene-2-iminothiazolidin-4-ones - Convenient Starting Compounds for Stereoselective Synthesis of Novel Dispirooxindole Derivatives
ChemistrySelect(2022)
Abstract
A convenient method for the synthesis of novel dispirooxindoles containing 2-iminothiazolidin-4-one moiety has been proposed. The method relies on a 1,3-dipolar cycloaddition of azomethine ylides generated in situ from paraformaldehyde and N-alkyl amino acids including chiral ones to 5-indolylidene-2-iminothiazolidin-4-ones. The method is suitable for preparing enantiomerically pure derivatives.
MoreTranslated text
Key words
2-iminothiazolidin-4-one,5-indolylidene-2-iminothiazolidin-4-one,azomethine ylide,1,3-dipolar cycloaddition,dispirooxindole
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined