Role of natural plant products against Hemagglutinin-esterase (HE) of human coronavirus

Background: COVID-19 has spread worldwide and become a great cause of economic and social loss. Due to the non-availability of effective medicine/drug, its control has become a difficult task. Objective: In the present study, the effect of some selected natural plant products was studied on the Hemagglutinin-esterase of the human coronavirus by performing molecular docking. Methods: Molecular docking study for some selected natural plant products against Hemagglutinin-esterase (HE) human coronavirus was performed using HEX 8.0.0 software. Results: The free energy of binding ranges from -298.14 to -161, curcumin being the highest. Conclusions: The results suggest that the natural plant products could act as possible anti-viral agents and maybe used as possible natural therapeutic agents.