Efficacy of nano-hydroxyapatite coating on osseointegration of early loaded dental implants

Objectives:The aim of the present study is to evaluate the efficacy of Nano hydroxyapatite coating onosseointegration of early loaded dental implants in posterior maxilla. Patients and Methods: A clinical trial was carried out on twelve early loaded implants in 3 males and 7 femalepatients with ages ranging from 20 to 45years A root-form implant is the most frequently used type of dental implant today. The basis for dental implants is osseointegration, in which osteoblasts grow and directly integratewith Nanohydroxyapatite coating surfacetitanium posts surgically embedded into the jaw. After implant placement all implants were evaluated clinically at 3, 6 months and 12 months after loading and radiographically CBCT scan was taken at immediately after installation and 6 months after loading time. Clinical (implant stability using Osstell ISQ device, probing pocket depth PPD and modified sulcus bleeding index mSBI) and radiographic parameters at6 months after loading time (marginal bone loss MBL) were assessed. During the first year interval, no implant was lost and all patients showed favorable clinical and radiographic finding. Results: During the first year interval, no implant was lost and all patients showed favorable clinical and radiographic finding. The statistical tests showed that there were statistical significant differences in the mean values of the primary outcome (implant stability measured by Ostell device),probing pocket depth PPD, and marginal bone loss between the patients implants over time. Besides, no significant differences were observed between patients regarding the secondary outcomes which include modified sulcus bleeding index mSBI. Conclusions: Early loading of implant with coating Nano hydroxyapatite could be considered a valuable option to replace missing teeth.To the best of our knowledge, early loaded implants with nano HA coating have shown encouraging results in a stronger and favorable regeneration of bone and better osseointegration of implants.