Electrogenerated chemiluminescence of a Ru(bpy)₃²⁺/arginine system: a specific and sensitive detection of acetaminophen

We use arginine as an alternative co-reactant for Ru(bpy)32+ by taking advantage of its low cost, non-toxicity, and biocompatibility. It is promising to expand the scope of the Ru(bpy)32+/Arg system and move forward their applications in bioassays.