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Unsupervised Cluster Analysis of Nasal Cytokines During RV Infection Identifies Distinct Immunophenotypes in Both Children and Adults with Allergic Asthma

Lyndsey Muehling,Peter Heymann, Holly Carper,Deborah Murphy,Joshua Kennedy,Stephen Early,Mauel Soto-Quiros,Lydiana Avila,Lisa Workman,Thomas Platts-Mills,Judith Woodfolk

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY（2022）

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Abstract
Infection with rhinovirus (RV) is a major risk factor for disease exacerbations in patients with allergic asthma. In this study we sought to identify nasal cytokine immunophenotypes that link to virus-induced episodes in children and adults.
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nasal cytokines,allergic asthma
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