Comparative treatment scheme between nitrofurantoin and ampicillin in pregnant patients 12 to 16 weeks, gestation with asymptomatic bacteriuria

Betty Sarabia-Alcocer,Baldemar Aké-Canché,Román Pérez-Balan,Rafael Manuel de Jesús Mex-Álvarez, Eduardo Jahir Gutiérrez Alcántara, Pedro Gerbacio Canul Rodríguez,María Eugenia López-Caamal,María Concepción Ruíz de Chávez-Figueroa, Carmen Cecilia Lara-Gamboa, Patricia Margarita Garma-Quen, Marvel del Carmen Valencia Gutiérrez, Judith Ruíz Hernández

Revista Ciencias de la Salud(2022)

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Abstract
Urinary tract infection is a frequent cause of demand for care in family medicine, it can have a significant participation in maternal and neonatal morbidity. Objective. To compare the treatment scheme 7 with the antibiotic ampicillin in cases of asymptomatic bacteriuria in pregnant women with 12 to 16 weeks of gestation against nitrofurantoin. Material and methods. Observational, cross-sectional, retrospective and analytical study conducted in pregnant patients between weeks 12 and 16 of gestation with asymptomatic bacteriuria. Result. In patients with asymptomatic bacteriuria, a greater persistence of the infection was found when being treated with nitrofurantoin. Pregnant patients with 13 weeks had the highest incidence of asymptomatic bacteriuria with a frequency of 31.82 %. Conclusions. Nitrofurantoin may be considered a better treatment option than ampicillin, given its lower incidence rate of asymptomatic bacteriuria in pregnant patients at 12 to 16 weeks' gestation.
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Key words
ampicillin,nitrofurantoin,pregnant patients,asymptomatic bacteriuria,gestation
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