Perspective for using 2,6-dimethylpyridine-N-oxide to reduce the toxic effect of xenobiotics in mammals
Journal Of Advanced Pharmacy Education And Research（2022）
Abstract
This work aimed to study the isolated and subsequent effects of 2,6-Dimethylpyridine-N-oxide (Ivin) and 2,4-D-2-EHE on the survival of rats and the population characteristics of the total mRNA that implements molecular genetic processes in rats. The studies on Wistar Han (SPF) rats were performed. It was found that Ivin at doses of 13 and 0.013 mg/kg bw, corresponding to 1/100 and 1/100000 DL50, does not cause clinical signs of intoxication in rats. Ivin increases the level of hybridization in m
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Key words
xenobiotics,toxic effect,dimethylpyridine-n-oxide
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